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GERD
During Pregnancy*
Heartburn is a frequent occurrence during pregnancy. It is thought to be due
to mechanical as well as hormonal changes. Lifestyle modifications and over-the-counter
antacids are safe. H2-RA group of medications should only
be used under the advice of a physician who would weigh the benefits and risks;
however, they are generally considered safe - Pregnancy Category B - except
for nizatidine [Axid] that is Category C. PPIs are Category C with the
exception of lansoprazole which is considered Category B (and according
to its manufacturer "should be used during pregnancy only if clearly needed").
* The following table describes teratogenic risk-factors as
defined by the US Food and Drug Administration:
Category Description
of Risk
A Controlled
studies show no risk
B No
evidence of risk in humans
C Risk
cannot be ruled out
D Positive
human evidence of fetal risk
X Contraindicated
in pregnancy
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